Genetic epidemiology

 


Effects of Physical Activity on Lipid Profile, according to apoE & CETP polymorphisms

Publications:

Bernstein MS, Costanza MC, James RW, Morris MA, Cambien F, Raoux S, Morabia A.
Physical activity may modulate the effects of APOE genotype on the lipid profile.
Arterioscler Thromb Vasc Biol 2002; 22: 133-140.

Bernstein MS, Costanza MC, James RW, Morris MA, Cambien F, Raoux S, Morabia A. No physical activity x CETP 1b.-629 interaction effects on lipid profile.
Med Sci Sports Exerc 2003;35(7):1124-9.

Correlation of blood lipid levels to genes sampled from the reverse cholesterol pathway and to environmental factors.

The HDL project is a collaborative project between the Division of clinical epidemiology and the Columbia Genome Center, New York.

Description

Publications

Morabia A, Cayanis E, Costanza MC, Ross BM, Flaherty MS, Alvin GB, Das K, Gilliam TC. Association of Extreme Blood Lipid Profile Phenotypic Variation with 11 Reverse Cholesterol Transport Genes and 10 Nongenetic Cardiovascular Disease Risk Factors (full text).
Hum Mol Genet 2003;12(21):2733-2743. Tables, Figure A and B

Morabia A, Cayanis E, Costanza MC, Ross BM, Bernstein MS, Flaherty MS, Alvin GB, Das K, Morris MA, Penchaszadeh GK, Zhang P, Gilliam TC.
Association between lipoprotein lipase (LPL) gene and blood lipids: a common variant for a common trait?
Genet Epidemiol 2003; 24:309-321. Appendices

 


These projects were funded by the Swiss National Science Foundation (N° 3200-054097 and 3200-068275.02). The survey was be conducted in 1999-2001

 

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